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This cutting-edge peptide from Peptides Supply is known for its ability to support tissue healing and repair. Research conducted on rodents and cultured cells indicates that it possesses the ability to promote tissue healing without any reported adverse effects in rodents.
Derived from a larger protein naturally found in the human digestive tract, BPC-157, also known as Body Protection Compound-157, is a peptide with intriguing properties. Similar to a pharmacologist, synthetic BPC-157 is composed of 15 amino acids and has been discovered to possess numerous healing properties that are reminiscent of its original compound.
Research has demonstrated that BPC-157 has a significant impact on various aspects of the body, including wound healing, blood vessel growth, the coagulation cascade, nitric oxide generation, immune system function, gene expression, and hormone regulation. Here are a few instances of research conducted on BPC-157:
It has been observed that BPC-157 has a significant impact on the proliferation and migration of fibroblasts, both in culture and in vivo. The effect of this compound is dependent on the dosage, with higher doses leading to increased cell spread. As a specialist in the field, it’s important to note that fibroblasts play a crucial role in the process of wound healing. These remarkable cells are responsible for depositing various extracellular matrix proteins, such as collagen, fibrin, elastin, and others.
BPC-157 is a powerful angiogenic factor that enhances the proliferation and growth of endothelial cells, which are responsible for lining blood vessels. Research in rats demonstrates a significant increase in the rate of collateral blood vessel growth in the presence of ischemia due to the peptide. Research conducted on chicken embryos indicates that BPC-157 may enhance vascular growth by stimulating VEGFR2, a cell surface receptor involved in the nitric oxide signalling pathway.
BPC-157 enhances collateralization and increases fibroblast density in cases of tendon, ligament, and bone injury. Extensive research conducted on rat tendons, both in laboratory settings and in living organisms, has consistently demonstrated the superior healing properties of BPC-157 compared to hormones like bFGF, EGF, and VGF.
Studies conducted on rats have demonstrated that BPC-157 has the ability to counteract certain indicators of oxidative stress, such as nitric oxide and malondialdehyde (MDA). Research has shown that BPC-157 has the ability to reduce the production of reactive oxygen species in the gastrointestinal tract, making it a potent antioxidant.
Research has shown that BPC-157 can effectively mitigate the adverse effects of NSAIDs, psychiatric medications, and certain heart medications. Studies conducted on rats have demonstrated that BPC-157 has the potential to safeguard the heart against QTc prolongation, which can result in serious and potentially life-threatening arrhythmias.
Studies have indicated that adding BPC-157 to honey bees’ diet can help minimize the harm caused by the fungus Nosema ceranae in their gastrointestinal tracts, leading to improved hive survival rates.
BPC-157 functions by:
When injected, BPC-157 interacts with specific proteins in the body that play a role in regulating cellular functions, such as growth factors and receptors. It has been demonstrated to promote the growth of blood vessels and new tissue, which can assist in the healing process.
It’s worth noting that BPC-157 has alternative names:
PL 14736, PL-10 It’s important to note that BPC-157 should not be mistaken for TB-500.
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